September 3, 2014 at 12:18 am (Air, Alternative Medicine, DNA, Education, Genetics, Healing, Health, Medicine, Science Education)
Cigarette Smoke Exposure Impairs Pulmonary Bacterial Clearance and Alveolar Macrophage Complement-Mediated Phagocytosis of Streptococcus pneumoniae
Cigarette smoke exposure increases the risk of pulmonary and invasive infections caused by Streptococcus pneumoniae, the most commonly isolated organism from patients with community-acquired pneumonia. Despite this association, the mechanisms by which cigarette smoke exposure diminishes host defense against S. pneumoniae infections are poorly understood. In this study, we compared the responses of BALB/c mice following an intratracheal challenge with S. pneumoniae after 5 weeks of exposure to room air or cigarette smoke in a whole-body exposure chamber in vivo and the effects of cigarette smoke on alveolar macrophage phagocytosis of S. pneumoniae in vitro. Bacterial burdens in cigarette smoke-exposed mice were increased at 24 and 48 h postinfection, and this was accompanied by a more pronounced clinical appearance of illness, hypothermia, and increased lung homogenate cytokines interleukin-1β (IL-1β), IL-6, IL-10, and tumor necrosis factor alpha (TNF-α). We also found greater numbers of neutrophils in bronchoalveolar lavage fluid recovered from cigarette smoke-exposed mice following a challenge with heat-killed S. pneumoniae. Interestingly, overnight culture of alveolar macrophages with 1% cigarette smoke extract, a level that did not affect alveolar macrophage viability, reduced complement-mediated phagocytosis of S. pneumoniae, while the ingestion of unopsonized bacteria or IgG-coated microspheres was not affected. This murine model provides robust additional support to the hypothesis that cigarette smoke exposure increases the risk of pneumococcal pneumonia and defines a novel cellular mechanism to help explain this immunosuppressive effect.
Full Article: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825918/
August 23, 2014 at 4:24 am (Art)
August 23, 2014 at 1:51 am (Art)
Tags: comedy, jack black
June 4, 2014 at 10:19 pm (Air, Alternative Medicine, anuraagah, Art, Attainment of the Dao, ॐ, Balance, Biology, Chakras, Chi Gung, Dalai Lama, Earth, Education, Energy, Equanimity, 道, Genetics, Global Warming, Globalization, Healing, Herbal Medicine, Hinduism, Homer, Internal Arts, Islam, Judaism, Learning disorders, Liberation, Matter, Meditation, Motivation, Nei Kung, Philosophy, Prayer, Quantum Physics, religion, Revolutionary, Science Education, Spiritual, Taiji Chuan, the "gods", the Divine, the garden, the LORD of ALL, the power that commands the universe, the Source of all life, Tibet, Traditional Chinese Medicine, Virtue, Wood, World Scriptures, Yang, zombie apocalypse, Zoology)
Just some thoughts…
How much does mental health impact physical health?
If we consider the emotional state of an individual who has just received news that a close loved one has suddenly died, most people would respond in a state of sadness and sorrow. In times of extreme grief, the impact of the mind on the body can be harsh and long lasting. In grief, despair, and sorrow, the mind is “sick.” The body naturally embodies the sickness, as a shadow follows one walking in light.
If that person were able to gain command over his or her mind, he or she would come to make peace with all reality and settle into a balanced and healthy state of mind functioning in good mental and physical health.
Cultivating a more focused mind, harmoniously aligned with the universal laws of morality, will allow greater consciousness expansion and intellectual development.
Overcoming grief requires liberation from false ideas. Letting go of all despair and finding peace is difficult for most people. Many people suffer miserably with bad health, physically and mentally.
Understanding the mysteries of life will enable people to take control of their health and well being. Knowledge is power. The truth removes the barriers of growth and allows an avenue for one to attain total freedom and liberation. Bringing our emotional minds into a harmonious balance will help us transcend all sickness. As in the example of the person receiving news of a loved one’s death, this person may fall into extreme despair and this can lead to destruction. However if one knew that no one really dies, then one would have no need to fall into a state of extreme despair/suffering.
Maintaining regular exercise will help one begin to regulate and balance the bodily system. Focusing on good health and being disciplined will provide an opportunity for positive change. When done in a harmonious manner, exercise will help one rise up from despair and relax. Most people suffer from varying degrees of stress and all the reasons for it. Being aware of this, the way to overcoming it is to focus on regulating all stress through elimination and balancing the mind in equanimity. Relaxing all tension, letting all stress go. Gently and with grace.
Understanding the difference between the body and the mind will allow one to attain a greater command of one’s health if one is disciplined enough to maintain discipline. It requires work, not too much, not too little.
Aligning one’s mind with the living power that sustains all life will allow one to begin to know the creator of reality and this leads to the highest end. It is mighty and powerful, and it is silent and elusive.